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Symbol
Name
ID
Abcb1a
ATP-binding cassette, sub-family B member 1A
MGI:97570
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Abnormality of blood and blood-forming tissues
Anemia
Neutrophilia
Leukocytosis
Abnormal granulocyte morphology
Abnormal basophil morphology
Acute lymphoblastic leukemia
Ph-positive acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemias
Chronic myelogenous leukemia
Myeloproliferative disorder
Superficial thrombophlebitis
Hyperfibrinogenemia
Thrombocytopenia
Thrombocytosis
Lymphoma
Elevated erythrocyte sedimentation rate
Splenomegaly
Disease(s) Associated with ABCB1
acute lymphoblastic leukemia
Behcet's disease
chronic myeloid leukemia
familial mediterranean fever
malaria

Mouse Phenotypes
increased eosinophil cell number
decreased gamma-delta intraepithelial T cell number
abnormal CD8 positive, alpha-beta intraepithelial T cell morphology
abnormal lymphocyte physiology
increased IgA level
increased IgE level
increased IgG1 level
increased IgG2a level
increased IgG2b level
increased IgG2 level
increased IgG3 level
increased IgM level
increased immunoglobulin level
Availability Mouse Genotype
Abcb1amds/Abcb1amds
Abcb1atm1Bor/Abcb1atm1Bor

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory